Protein phosphatase 2A dysfunction in Alzheimer’s disease

Protein Phosphatase 2A (PP2A) is a large family of enzymes that account for the majority of brain Ser/Thr phosphatase activity. While PP2A enzymes collectively modulate most cellular processes, sophisticated regulatory mechanisms are ultimately responsible for ensuring isoform-specific substrate spe...

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Bibliographic Details
Main Authors: Jean-Marie eSontag, Estelle eSontag
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
tau
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00016/full