A Novel Prognostic Marker for Primary CNS Lymphoma: Lactate Dehydrogenase-to-Lymphocyte Ratio Improves Stratification of Patients Within the Low and Intermediate MSKCC Risk Groups

A Novel Prognostic Marker for Primary CNS Lymphoma: Lactate Dehydrogenase-to-Lymphocyte Ratio Improves Stratification of Patients Within the Low and Intermediate MSKCC Risk Groups

BackgroundPrimary central nervous system lymphoma (PCNSL) is a highly aggressive and rare extranodal non-Hodgkin lymphoma (NHL). The MSKCC and the IELSG scores represent the most widely used prognostic models, but many changes have occurred in therapeutic protocols since their development. Moreover,...

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Bibliographic Details
Main Authors: Yuting Gao, Li Wei, Seok Jin Kim, Liang Wang, Yingzhi He, Yanfang Zheng, Luca Bertero, Alessia Pellerino, Paola Cassoni, Luca Tamagnone, Prochazka Katharina Theresa, Alexander Deutsch, Huien Zhan, Jing Lai, Yao Wang, Hua You
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
primary central nervous system lymphoma
lactate dehydrogenase-to-lymphocyte ratio
prognostic parameter
Memorial Sloan Kettering Cancer Center (MSKCC) score
neutrophil-to-lymphocyte ratio
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.696147/full

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