An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites

Abstract Background Bone marrow (BM) niches are often inaccessible for controlled experimentation due to their difficult accessibility, biological complexity, and three-dimensional (3D) geometry. Methods Here, we report the development and characterization of a BM model comprising of cellular and st...

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Bibliographic Details
Main Authors: Mónica S. Ventura Ferreira, Christian Bergmann, Isabelle Bodensiek, Kristina Peukert, Jessica Abert, Rafael Kramann, Paul Kachel, Björn Rath, Stephan Rütten, Ruth Knuchel, Benjamin L. Ebert, Horst Fischer, Tim H. Brümmendorf, Rebekka K. Schneider
Format: Article
Language:English
Published: BMC 2016-01-01
Series:Journal of Hematology & Oncology
Online Access:http://link.springer.com/article/10.1186/s13045-016-0234-9