The β-Blocker Carvedilol Prevented Ultraviolet-Mediated Damage of Murine Epidermal Cells and 3D Human Reconstructed Skin

The β-Blocker Carvedilol Prevented Ultraviolet-Mediated Damage of Murine Epidermal Cells and 3D Human Reconstructed Skin

The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precursor event in skin carcinogenesis. The effects of...

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Bibliographic Details
Main Authors: Mengbing Chen, Sherry Liang, Ayaz Shahid, Bradley T. Andresen, Ying Huang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
carcinogenesis
chemoprevention
β-blocker
carvedilol
ultraviolet
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ros
cpd
pge<sub>2</sub>
Online Access:https://www.mdpi.com/1422-0067/21/3/798

Internet

https://www.mdpi.com/1422-0067/21/3/798

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