COVID‐19: emergence and mutational diversification of SARS‐CoV‐2

COVID‐19: emergence and mutational diversification of SARS‐CoV‐2

Summary The origin of the SARS‐CoV‐2 virus is not yet defined, but a viral zoonosis from bats – with or without an alternative animal as an intermediate host – is still the most likely hypothesis. The intensive virological and epidemiological research combined with massive sequencing efforts of whol...

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Main Author: Harald Brüssow
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.13800
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spelling doaj-4ffe74c9c64d4c25b8cf402b11df2c342021-04-30T10:22:41ZengWileyMicrobial Biotechnology1751-79152021-05-0114375676810.1111/1751-7915.13800COVID‐19: emergence and mutational diversification of SARS‐CoV‐2Harald Brüssow0Laboratory of Gene Technology Department of Biosystems KU Leuven Leuven BelgiumSummary The origin of the SARS‐CoV‐2 virus is not yet defined, but a viral zoonosis from bats – with or without an alternative animal as an intermediate host – is still the most likely hypothesis. The intensive virological and epidemiological research combined with massive sequencing efforts of whole viral genomes allowed an unprecedented analysis of an unfolding pandemic at the level of viral evolution with the documentation of extinction events, prevalence increases and rise to dominance for different viral lineages that provide not only fundamental insights into mechanisms of viral evolution, but influence also public health measures to contain the virus.https://doi.org/10.1111/1751-7915.13800
collection DOAJ
language English
format Article
sources DOAJ
author Harald Brüssow
spellingShingle Harald Brüssow
COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
Microbial Biotechnology
author_facet Harald Brüssow
author_sort Harald Brüssow
title COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
title_short COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
title_full COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
title_fullStr COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
title_full_unstemmed COVID‐19: emergence and mutational diversification of SARS‐CoV‐2
title_sort covid‐19: emergence and mutational diversification of sars‐cov‐2
publisher Wiley
series Microbial Biotechnology
issn 1751-7915
publishDate 2021-05-01
description Summary The origin of the SARS‐CoV‐2 virus is not yet defined, but a viral zoonosis from bats – with or without an alternative animal as an intermediate host – is still the most likely hypothesis. The intensive virological and epidemiological research combined with massive sequencing efforts of whole viral genomes allowed an unprecedented analysis of an unfolding pandemic at the level of viral evolution with the documentation of extinction events, prevalence increases and rise to dominance for different viral lineages that provide not only fundamental insights into mechanisms of viral evolution, but influence also public health measures to contain the virus.
url https://doi.org/10.1111/1751-7915.13800
work_keys_str_mv AT haraldbrussow covid19emergenceandmutationaldiversificationofsarscov2
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