Tr1-like T cells- an enigmatic regulatory T cell lineage

Tr1-like T cells- an enigmatic regulatory T cell lineage

The immune system evolved to respond to foreign invaders and prevent autoimmunity to self-antigens. Several types of regulatory T cells facilitate the latter process. These include a subset of Foxp3- CD4+ T cells able to secrete IL-10 in an antigen-specific manner, type 1 regulatory (Tr1) T cells. A...

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Bibliographic Details
Main Authors: Anna Malgorzata White, David Cameron Wraith
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Peripheral Tolerance
IL-10
inhibitory receptors
CD4+ T cell
Tr-1 T cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00355/full

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