Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?

Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?

Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular matrix proteins. Widely expressed, they mediate many biological activities, including angiogenesis, blood coagulation, devel...

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Bibliographic Details
Main Authors: Valeria Cagno, Eirini D. Tseligka, Samuel T. Jones, Caroline Tapparel
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Viruses
Subjects:
viral attachment receptor
heparan sulfate proteoglycans
HSPG
syndecans
glypicans
viral adaptation
intra-host adaptation
tropism
broad-spectrum antivirals
viral binding
Online Access:https://www.mdpi.com/1999-4915/11/7/596

Internet

https://www.mdpi.com/1999-4915/11/7/596

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