Tetrahydrobiopterin Improves Endothelial Function in Cardiovascular Disease: A Systematic Review

Background. Tetrahydrobiopterin (BH4) is a cofactor of nitric oxide synthase (NOS). Nitric oxide (NO) bioavailability is reduced during the early stage of vascular diseases, such as coronary artery disease, hypercholesterolemia, hypertension, and diabetic vasculopathy, and even throughout the entire...

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Bibliographic Details
Main Authors: Qiongying Wang, Mina Yang, Han Xu, Jing Yu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/850312