Allopurinol reverses mercaptopurine-induced hypoglycemia in patients with acute lymphoblastic leukemia [version 2; peer review: 2 approved]

Fasting hypoglycemia is a known complication of mercaptopurine (6MP) maintenance therapy for acute lymphoblastic leukemia (ALL). It is associated with high levels of the methylated metabolite 6-methyl-mercaptopurine (6MMP). Symptoms of hypoglycemia include morning tremulousness, nausea and vomiting....

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Bibliographic Details
Main Authors: Melissa Zhang, Bruce Bostrom
Format: Article
Language:English
Published: F1000 Research Ltd 2019-11-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-176/v2