NLRP3/Caspase-1 inflammasome activation is decreased in alveolar macrophages in patients with lung cancer.

Lung cancer (LC) remains the leading cause of cancer-related mortality. The interaction of cancer cells with their microenvironment, results in tumor escape or elimination. Alveolar macrophages (AMs) play a significant role in lung immunoregulation, however their role in LC has been outshined by the...

Full description

Bibliographic Details
Main Authors: Ismini Lasithiotaki, Eliza Tsitoura, Katerina D Samara, Athina Trachalaki, Irini Charalambous, Nikolaos Tzanakis, Katerina M Antoniou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6203254?pdf=render