Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies
An elevated serum level of NM23-H1 protein is a poor prognostic factor in patients with various hematologic malignancies. The extracellular NM23-H1 protein promotes the in vitro growth and survival of acute myelogenous leukemia (AML) cells and inversely inhibits the in vitro survival of normal perip...
Main Authors: | Junko Okabe-Kado, Takashi Kasukabe, Yasuhiko Kaneko |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2012/879368 |
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