Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives

Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives

In the present study, various amides of 2-amino-5-(4-methylphenyl)-diazenyl-4-phenyl-1, 3-thiazole was synthesized and their biological activities were evaluated. All the synthesized compounds were characterized by the combination of elemental analysis and standard spectroscopic methods. They are sc...

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Main Authors: Ashishkumar Kantilal Prajapati, Vishal Pankajkumar Modi
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
aminothiazole derivatives
amide linkage
microbial activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500008&lng=en&tlng=en
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spelling doaj-4fdf45f63c6a4a319b0b1649c9b8ee602020-11-25T00:03:37ZengSociedade Brasileira de QuímicaQuímica Nova1678-70642011-01-0134577177410.1590/S0100-40422011000500008S0100-40422011000500008Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivativesAshishkumar Kantilal Prajapati0Vishal Pankajkumar Modi1University of BarodaUniversity of BarodaIn the present study, various amides of 2-amino-5-(4-methylphenyl)-diazenyl-4-phenyl-1, 3-thiazole was synthesized and their biological activities were evaluated. All the synthesized compounds were characterized by the combination of elemental analysis and standard spectroscopic methods. They are screened for anti-bacterial activity against Escherichia coli and Staphylococcus aureus as well as screened for antifungal activity against Aspergillus niger and Apergillus oryzae by cup plate method at 1 µg/ mL concentration in DMF.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500008&lng=en&tlng=enaminothiazole derivativesamide linkagemicrobial activity
collection DOAJ
language English
format Article
sources DOAJ
author Ashishkumar Kantilal Prajapati
Vishal Pankajkumar Modi
spellingShingle Ashishkumar Kantilal Prajapati
Vishal Pankajkumar Modi
Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
Química Nova
aminothiazole derivatives
amide linkage
microbial activity
author_facet Ashishkumar Kantilal Prajapati
Vishal Pankajkumar Modi
author_sort Ashishkumar Kantilal Prajapati
title Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
title_short Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
title_full Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
title_fullStr Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
title_full_unstemmed Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
title_sort synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives
publisher Sociedade Brasileira de Química
series Química Nova
issn 1678-7064
publishDate 2011-01-01
description In the present study, various amides of 2-amino-5-(4-methylphenyl)-diazenyl-4-phenyl-1, 3-thiazole was synthesized and their biological activities were evaluated. All the synthesized compounds were characterized by the combination of elemental analysis and standard spectroscopic methods. They are screened for anti-bacterial activity against Escherichia coli and Staphylococcus aureus as well as screened for antifungal activity against Aspergillus niger and Apergillus oryzae by cup plate method at 1 µg/ mL concentration in DMF.
topic aminothiazole derivatives
amide linkage
microbial activity
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500008&lng=en&tlng=en
work_keys_str_mv AT ashishkumarkantilalprajapati synthesisandbiologicalactivityofn54methylphenyldiazenyl4phenyl13thiazol2ylbenzamidederivatives
AT vishalpankajkumarmodi synthesisandbiologicalactivityofn54methylphenyldiazenyl4phenyl13thiazol2ylbenzamidederivatives
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