Heat Shock Protein Inspired Nanochaperones Restore Amyloid‐β Homeostasis for Preventative Therapy of Alzheimer's Disease

Heat Shock Protein Inspired Nanochaperones Restore Amyloid‐β Homeostasis for Preventative Therapy of Alzheimer's Disease

Abstract Amyloid beta (Aβ) aggregation is generally believed as the crucial and primary cause of Alzheimer's disease (AD). However, current Aβ‐targeted therapeutic strategies show limited disease‐modifying efficacy due to the irreversible damages in the late stage of AD, thus the treatment shou...

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Bibliographic Details
Main Authors: Huiru Yang, Xinyu Li, Lin Zhu, Xiaohui Wu, Shaozhi Zhang, Fan Huang, Xizeng Feng, Linqi Shi
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Advanced Science
Subjects:
Alzheimer's disease
amyloid beta peptides
polymeric micelles
precaution
self‐assembly nanochaperones
Online Access:https://doi.org/10.1002/advs.201901844

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