Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness.

Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness.

<h4>Background</h4>Practical methods of monitoring innate immune mucosal responsiveness are lacking. Lipopolysaccharide (LPS) is a component of the cell wall of Gram negative bacteria and a potent activator of Toll-like receptor (TLR)-4. To measure LPS responsiveness of the nasal mucosa,...

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Bibliographic Details
Main Authors: Jaideep Dhariwal, Jeremy Kitson, Reema E Jones, Grant Nicholson, Tanushree Tunstall, Ross P Walton, Grace Francombe, Jane Gilbert, Andrew J Tan, Robert Murdoch, Onn Min Kon, Peter J Openshaw, Trevor T Hansel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0135363

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