The impact of paced QRS duration on the expression of genes related to contractile function of the left ventricle in chronically paced patients from the right ventricular apex

The impact of paced QRS duration on the expression of genes related to contractile function of the left ventricle in chronically paced patients from the right ventricular apex

Background: Right ventricular (RV) apex has proven to induce abnormal left ventricular (LV) activation pattern leading to pacing-induced cardiomyopathy (PICM) in a substantial percentage of paced patients. This study assessed the impact of paced QRS duration on the expression in the peripheral blood...

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Bibliographic Details
Main Authors: Εmmanuel Simantirakis, Eva Arkolaki, Joanna Kontaraki, Gregory Chlouverakis, Hercules Mavrakis, Eleutherios Kallergis, Fragiskos Parthenakis, Panos Vardas
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Hellenic Journal of Cardiology
Subjects:
Right ventricular apical pacing
Gene expression
SERCA
LV remodelling
Online Access:http://www.sciencedirect.com/science/article/pii/S1109966619300028

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