Precision Engineering of the Transcription Factor Cre1 in Hypocrea jecorina (Trichoderma reesei) for Efficient Cellulase Production in the Presence of Glucose

Precision Engineering of the Transcription Factor Cre1 in Hypocrea jecorina (Trichoderma reesei) for Efficient Cellulase Production in the Presence of Glucose

In Trichoderma reesei, carbon catabolite repression (CCR) significantly downregulates the transcription of cellulolytic enzymes, which is usually mediated by the zinc finger protein Cre1. It was found that there is a conserved region at the C-terminus of Cre1/CreA in several cellulase-producing fung...

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Bibliographic Details
Main Authors: Lijuan Han, Yinshuang Tan, Wei Ma, Kangle Niu, Shaoli Hou, Wei Guo, Yucui Liu, Xu Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
carbon catabolite repression
transcription factor
Cre1
cellulase
phosphorylation
Trichoderma reesei
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00852/full

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