Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis

Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis

The clinical outcomes of hepatocellular carcinoma (HCC) remain dismal. Elucidating the molecular mechanisms for the progression of aggressive HCC holds the promise for developing novel intervention strategies. The transactivation response element RNA-binding protein (TRBP/TARBP2), a key component of...

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Bibliographic Details
Main Authors: Li-Man Li, Chang Chen, Ruo-Xi Ran, Jing-Tao Huang, Hui-Lung Sun, Chang Zeng, Zhou Zhang, Wei Zhang, Song-Mei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
HCC
TARBP2
miR-145
SERPINE1
progression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.620912/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.620912/full

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