Synthesis of 4-Substituted-1,2-Dihydroquinolines by Means of Gold-Catalyzed Intramolecular Hydroarylation Reaction of <i>N</i>-Ethoxycarbonyl-<i>N</i>-Propargylanilines

Synthesis of 4-Substituted-1,2-Dihydroquinolines by Means of Gold-Catalyzed Intramolecular Hydroarylation Reaction of <i>N</i>-Ethoxycarbonyl-<i>N</i>-Propargylanilines

An alternative Au(I)-catalyzed synthetic route to functionalized 1,2-dihydroquinolines is reported. This novel approach is based on the use of <i>N</i>-ethoxycarbonyl protected-<i>N</i>-propargylanilines as building blocks that rapidly undergo the IMHA reaction affording the...

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Bibliographic Details
Main Authors: Antonio Arcadi, Andrea Calcaterra, Giancarlo Fabrizi, Andrea Fochetti, Antonella Goggiamani, Antonia Iazzetti, Federico Marrone, Vincenzo Marsicano, Giulia Mazzoccanti, Andrea Serraiocco
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
gold catalysis
intramolecular hydroarylation
1,2-dihydroquinolines
Online Access:https://www.mdpi.com/1420-3049/26/11/3366

Internet

https://www.mdpi.com/1420-3049/26/11/3366

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