Monitoring Theophylline Concentrations in Saline Using Terahertz ATR Spectroscopy
To assess the possibility of terahertz technology for the determination of drug concentration in blood, we endeavored to apply a terahertz (THz) attenuated total reflection (ATR) method to measure the levels of theophylline in saline. A change in reflected THz wave amplitude was observed in a theoph...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-03-01
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| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3417/6/3/72 |
| Summary: | To assess the possibility of terahertz technology for the determination of drug concentration in blood, we endeavored to apply a terahertz (THz) attenuated total reflection (ATR) method to measure the levels of theophylline in saline. A change in reflected THz wave amplitude was observed in a theophylline concentration-dependent manner. This result was obtained with simple measurements of comparisons of the amplitude of the reflected wave, and suggests that it is possible to monitor concentration changes of drugs in liquid material using THz ATR measurements. |
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| ISSN: | 2076-3417 |