THE ALGORITHM OF COMPLEX SYNDROME-ORIENTED THERAPY IN CHILDREN WITH CYSTIC FIBROSIS: A MODERN APPROACH
Cystic fibrosis is a disease, which involves multiple organs and systems, and treatment of this disorder requires a complex approach (combination of medicinal and non-medicinal methods). Specialized medical care in centers for cystic fibrosis treatment allows to improve the patients’ rates of surviv...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2013-09-01
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| Series: | Voprosy Sovremennoj Pediatrii |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/277 |
| Summary: | Cystic fibrosis is a disease, which involves multiple organs and systems, and treatment of this disorder requires a complex approach (combination of medicinal and non-medicinal methods). Specialized medical care in centers for cystic fibrosis treatment allows to improve the patients’ rates of survivability and quality of life. This article contains information on the main drugs used nowadays in cystic fibrosis therapy. The authors describe the special characteristics of dornase alfa use in children of various age groups and detail the effects of this drug: powerful mucolytic, anti-inflammatory and antibacterial actions. The rationality of including of this drug into the basic therapy both with preventative and medicinal aims as soon as a patient is diagnosed with cystic fibrosis is substantiated. It is shown, that in cases of chronic Pseudomonas aeruginosa infections a patient’s condition can be stabilized with the means of continual tobramycin or sodium colistimethate inhalations, as well as the new powder form of tobramycin. It was noted, that in cystic fibrosis pancreatic enzyme can be effective only in forms of minimicrospheres. For the first time the new algorithm of complex treatment of this disease according to the symptoms and complications was offered by the authors. |
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| ISSN: | 1682-5527 1682-5535 |