Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting
Wildlife has often presented and suggested the effects of endocrine disrupting chemicals (EDCs). Animal studies have given us an important opportunity to understand the mechanisms of action of many chemicals on the endocrine system and on neurodevelopment and behaviour, and to evaluate the effects o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/19/6/1647 |
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doaj-4f7bdaf43cc34503b01da11dda700582 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Maria Elisabeth Street Sabrina Angelini Sergio Bernasconi Ernesto Burgio Alessandra Cassio Cecilia Catellani Francesca Cirillo Annalisa Deodati Enrica Fabbrizi Vassilios Fanos Giancarlo Gargano Enzo Grossi Lorenzo Iughetti Pietro Lazzeroni Alberto Mantovani Lucia Migliore Paola Palanza Giancarlo Panzica Anna Maria Papini Stefano Parmigiani Barbara Predieri Chiara Sartori Gabriele Tridenti Sergio Amarri |
| spellingShingle |
Maria Elisabeth Street Sabrina Angelini Sergio Bernasconi Ernesto Burgio Alessandra Cassio Cecilia Catellani Francesca Cirillo Annalisa Deodati Enrica Fabbrizi Vassilios Fanos Giancarlo Gargano Enzo Grossi Lorenzo Iughetti Pietro Lazzeroni Alberto Mantovani Lucia Migliore Paola Palanza Giancarlo Panzica Anna Maria Papini Stefano Parmigiani Barbara Predieri Chiara Sartori Gabriele Tridenti Sergio Amarri Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting International Journal of Molecular Sciences Endocrine Disrupting Chemicals (EDCs) neurodevelopment autism obesity puberty fertility thyroid function epigenetics carcinogenesis growth |
| author_facet |
Maria Elisabeth Street Sabrina Angelini Sergio Bernasconi Ernesto Burgio Alessandra Cassio Cecilia Catellani Francesca Cirillo Annalisa Deodati Enrica Fabbrizi Vassilios Fanos Giancarlo Gargano Enzo Grossi Lorenzo Iughetti Pietro Lazzeroni Alberto Mantovani Lucia Migliore Paola Palanza Giancarlo Panzica Anna Maria Papini Stefano Parmigiani Barbara Predieri Chiara Sartori Gabriele Tridenti Sergio Amarri |
| author_sort |
Maria Elisabeth Street |
| title |
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting |
| title_short |
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting |
| title_full |
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting |
| title_fullStr |
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting |
| title_full_unstemmed |
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting |
| title_sort |
current knowledge on endocrine disrupting chemicals (edcs) from animal biology to humans, from pregnancy to adulthood: highlights from a national italian meeting |
| publisher |
MDPI AG |
| series |
International Journal of Molecular Sciences |
| issn |
1422-0067 |
| publishDate |
2018-06-01 |
| description |
Wildlife has often presented and suggested the effects of endocrine disrupting chemicals (EDCs). Animal studies have given us an important opportunity to understand the mechanisms of action of many chemicals on the endocrine system and on neurodevelopment and behaviour, and to evaluate the effects of doses, time and duration of exposure. Although results are sometimes conflicting because of confounding factors, epidemiological studies in humans suggest effects of EDCs on prenatal growth, thyroid function, glucose metabolism and obesity, puberty, fertility, and on carcinogenesis mainly through epigenetic mechanisms. This manuscript reviews the reports of a multidisciplinary national meeting on this topic. |
| topic |
Endocrine Disrupting Chemicals (EDCs) neurodevelopment autism obesity puberty fertility thyroid function epigenetics carcinogenesis growth |
| url |
http://www.mdpi.com/1422-0067/19/6/1647 |
| work_keys_str_mv |
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doaj-4f7bdaf43cc34503b01da11dda7005822020-11-25T00:57:19ZengMDPI AGInternational Journal of Molecular Sciences1422-00672018-06-01196164710.3390/ijms19061647ijms19061647Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian MeetingMaria Elisabeth Street0Sabrina Angelini1Sergio Bernasconi2Ernesto Burgio3Alessandra Cassio4Cecilia Catellani5Francesca Cirillo6Annalisa Deodati7Enrica Fabbrizi8Vassilios Fanos9Giancarlo Gargano10Enzo Grossi11Lorenzo Iughetti12Pietro Lazzeroni13Alberto Mantovani14Lucia Migliore15Paola Palanza16Giancarlo Panzica17Anna Maria Papini18Stefano Parmigiani19Barbara Predieri20Chiara Sartori21Gabriele Tridenti22Sergio Amarri23Department of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 48, 40126 Bologna, ItalyFormer Department of Medicine, University of Parma, Via A. Catalani 10, 43123 Parma, ItalyECERI European Cancer and Environment Research Institute, Square de Meeus, 38-40, 1000 Bruxelles, BelgiumPediatric Endocrinology Programme, Pediatrics Unit, Department of Woman, Child Health and Urologic Diseases, AOU S. Orsola-Malpighi, Via Massarenti, 11, 40138 Bologna, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Pediatrics (DPUO), Bambino Gesù Children’s Hospital, Tor Vergata University, Piazza S. Onofrio 4, 00165 Rome, ItalyDepartment of Pediatrics and Neonatology, Augusto Murri Hospital, Via Augusto Murri, 17, 63900 Fermo, ItlayNeonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, AOU and University of Cagliari, via Ospedale, 54, 09124 Cagliari, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyVilla Santa Maria Institute, Neuropsychiatric Rehabilitation Center, Via IV Novembre 15, 22038 Tavernerio (Como), ItalyDepartment of Medical and Surgical Sciences of the Mother, Children and Adults, Pediatrics Unit, University of Modena and Reggio Emilia, via del Pozzo, 71, 41124 Modena, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Veterinary Public Health and Food Safety, Food and Veterinary Toxicology Unit ISS–National Institute of Health, Viale Regina Elena 299, 00161 Rome, ItalyDepartment of Traslational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma, 55, 56123 Pisa, ItalyUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, Via Gramsci, 14, 43126 Parma, ItalyLaboratory of Neuroendocrinology, Department of Neuroscience Rita Levi Montalcini, University of Turin, Via Cherasco 15, 10126 Turin, ItalyDepartment of Chemistry ‘Ugo Schiff’, University of Florence, Via della Lastruccia, 3-13, 50019 Sesto Fiorentino, Florence, ItalyUnit of Evolutionary and Functional Biology—Department of Chemistry, Life Sciences and Environmental Sustainability (SCVSA)-University of Parma–11/a, 43124 Parma, ItalyDepartment of Medical and Surgical Sciences of the Mother, Children and Adults, Pediatrics Unit, University of Modena and Reggio Emilia, via del Pozzo, 71, 41124 Modena, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyWildlife has often presented and suggested the effects of endocrine disrupting chemicals (EDCs). Animal studies have given us an important opportunity to understand the mechanisms of action of many chemicals on the endocrine system and on neurodevelopment and behaviour, and to evaluate the effects of doses, time and duration of exposure. Although results are sometimes conflicting because of confounding factors, epidemiological studies in humans suggest effects of EDCs on prenatal growth, thyroid function, glucose metabolism and obesity, puberty, fertility, and on carcinogenesis mainly through epigenetic mechanisms. This manuscript reviews the reports of a multidisciplinary national meeting on this topic.http://www.mdpi.com/1422-0067/19/6/1647Endocrine Disrupting Chemicals (EDCs)neurodevelopmentautismobesitypubertyfertilitythyroid functionepigeneticscarcinogenesisgrowth |