Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation.

Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation.

Deregulation of mechanisms that control cell motility plays a key role in tumor progression by promoting tumor cell dissemination. Secreted netrins and their receptors, Deleted in Colorectal Cancer (DCC), neogenin, and the UNC5 homologues, regulate cell and axon migration, cell adhesion, and tissue...

Full description

Bibliographic Details
Main Authors:	Andrew A Jarjour, Margaret Durko, Tamarah L Luk, Nathalie Marçal, Masoud Shekarabi, Timothy E Kennedy
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3182204?pdf=render

Similar Items

Netrin-1 signaling : cellular consequences and molecular mechanisms
by: Shekarabi, Seyed Masoud
Published: (2003)

A multifunctional protein : Phosphoglucose isomerase / autocrine motility factory / neuroleukin
by: Y, Nathalie
Published: (2011)

Autocrine regulation of human sperm motility by tachykinins
by: Pinto Francisco M, et al.
Published: (2010-08-01)

Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts
by: Laura L. Stafman, et al.
Published: (2019-09-01)

Autocrine motility factor and its receptor expression in musculoskeletal tumors
by: Kosei Nakajima, et al.
Published: (2020-10-01)

Autocrine and paracrine factors in the control of gallbladder motility and gallstone pathogenesis
by: Greaves, Ralph Robert Sissak Handley
Published: (2001)

ARRESTINS REGULATE CELL SPREADING AND MOTILITY VIA FOCAL ADHESION DYNAMICS
by: Cleghorn, Whitney M
Published: (2012)

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility
by: Daniel Luxen, et al.
Published: (2017-02-01)

Function Of Autocrine Motility Factor Receptor (amfr) In The Epibolic Movement Of Zebrafish Gastrula
by: Ming-Hao Chiang, et al.
Published: (2013)

Autocrine motility factor promotes endometrial cancer progression by targeting GPER-1
by: Yiran Li, et al.
Published: (2019-03-01)

Alternative Splicing Transcripts and Developmental Expression of Autocrine Motility Factor Receptor in Zebrafish.
by: Yu-Ju Peng, et al.

The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-β1 and focal adhesion kinase activation
by: Andrea A. Villanueva, et al.
Published: (2021-01-01)

Netrin-1 marshals mitochondrial movement, morphology, and metabolism in myelin
by: Diane S Nakamura, et al.
Published: (2021-01-01)

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
by: Wang Wenqi, et al.
Published: (2011-11-01)

Thrombospondin 1, an autocrine regulator in T cell adhesion and migration
by: Li, ShuShun
Published: (2005)

The Expression of Netrin-1 in the Thymus and Its Effects on Thymocyte Adhesion and Migration
by: Xiao-Kai Guo, et al.
Published: (2013-01-01)

Amplification of autocrine motility factor and its receptor in multiple myeloma and other musculoskeletal tumors
by: Kosei Nakajima, et al.
Published: (2020-08-01)

Immunohistochemical expression of Type IV Collagen and Autocrine Motility Factor Receptor in Odontogenic Tumours
by: Harshaminder Kaur Grewal, et al.
Published: (2014-10-01)

Functional study of zebrafish autocrine motility factor receptor (amfr) during embryonic development
by: Chin - Wei Chang, et al.
Published: (2011)

Gene expression and function of autocrine motility factor receptor (amfr) during zebrafish development
by: Jia-Yi Deng, et al.
Published: (2009)

Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins.
by: Nichol L G Miller, et al.
Published: (2012-01-01)

Myxococcus xanthus gliding motors are elastically coupled to the substrate as predicted by the focal adhesion model of gliding motility.
by: Rajesh Balagam, et al.
Published: (2014-05-01)

Hyperexpressed netrin-1promoted neural stem cells migration in mice after focal cerebral ischemia
by: Haiyan Lu, et al.
Published: (2016-09-01)

The role of connexin43 in glioma motility
by: Bates, David Christopher
Published: (2010)

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A
by: Jing-Ying Chen, et al.
Published: (2017-07-01)

Divergence of the UNC-6/Netrin family; Molecular cloning and functional characterization of glycosyl phosphatidylinositol-linked netrin-G subfamily members, netrin-G1 and netrin-G2, which promote neurite outgrowth
by: Nakashiba, Toshiaki
Published: (2011)

The origin of the expressed retrotransposed gene ACTBL2 and its influence on human melanoma cells’ motility and focal adhesion formation
by: Natalia Malek, et al.
Published: (2021-02-01)

Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells.
by: Hery Urra, et al.
Published: (2012-01-01)

Netrins and Their Roles in Placental Angiogenesis
by: Mbarka Dakouane-Giudicelli, et al.
Published: (2014-01-01)

Mechanisms of Focal Adhesions
by: Saxena, Mayur
Published: (2018)

ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro
by: Del Valle Luis, et al.
Published: (2010-06-01)

A Focal Adhesion-Related Gene Signature Predicts Prognosis in Glioma and Correlates With Radiation Response and Immune Microenvironment
by: Haonan Li, et al.
Published: (2021-09-01)

Raft-dependent endocytosis of autocrine motility factor/phosphoglucose isomerase: a potential drug delivery route for tumor cells.
by: Liliana D Kojic, et al.
Published: (2008-01-01)

Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer
by: Ma YT, et al.
Published: (2018-10-01)

Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3
by: Marina N. Sharifi, et al.
Published: (2016-05-01)

Targeting focal adhesion signaling in cancer and acquired resistance to focal adhesion kinase inhibitors
by: Lougheed, Caroline
Published: (2010)

Studies of Tumor Cell Motility and Energy Demand in Glioma
by: Wei-Lan Yeh, et al.
Published: (2009)

Endocytosis, cell signalling, adhesion and motility
by: McMahon HT
Published: (2009-02-01)

Therapeutic effects of topical netrin-4 inhibits corneal neovascularization in alkali-burn rats.
by: Yun Han, et al.
Published: (2015-01-01)

The epithelial cell adhesion molecule (EpCAM) regulates cell motility and cell-cell adhesion by inhibiting PKC signaling
by: Maghzal, Nadim
Published: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8snumto94kuvipici5ba88k5oe