A versatile viral system for expression and depletion of proteins in mammalian cells.

A versatile viral system for expression and depletion of proteins in mammalian cells.

The ability to express or deplete proteins in living cells is crucial for the study of biological processes. Viral vectors are often useful to deliver DNA constructs to cells that are difficult to transfect by other methods. Lentiviruses have the additional advantage of being able to integrate into...

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Bibliographic Details
Main Authors: Eric Campeau, Victoria E Ruhl, Francis Rodier, Corey L Smith, Brittany L Rahmberg, Jill O Fuss, Judith Campisi, Paul Yaswen, Priscilla K Cooper, Paul D Kaufman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2717805?pdf=render

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