Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI
AcidoCEST magnetic resonance imaging (MRI) has previously been shown to measure tumor extracellular pH (pHe) with excellent accuracy and precision. This study investigated the ability of acidoCEST MRI to monitor changes in tumor pHe in response to therapy. To perform this study, we used the Granta 5...
Main Authors: | Paul J. Akhenblit PhD, Neale T. Hanke PhD, Alexander Gill BS, Daniel O. Persky MD, Christine M. Howison MS, Mark D. Pagel PhD, Amanda F. Baker PharmD, PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2016-04-01
|
Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1177/1536012116645439 |
Similar Items
-
Interrogating Tumor Metabolism with AcidoCEST MRI
by: Akhenblit, Paul
Published: (2016) -
Interrogating tumor energy metabolism with acidocest MRI
by: Akhenblit, Paul Joseph
Published: (2016) -
Extracellular acidosis differentiates pancreatitis and pancreatic cancer in mouse models using acidoCEST MRI
by: Rachel A. High, et al.
Published: (2019-11-01) -
Clinical Effects of Krachaidum (): A Systematic Review
by: Surasak Saokaew PharmD, PhD, et al.
Published: (2017-07-01) -
The Role of Date Palm ( L) Pollen in Fertility
by: Mohammad Tahvilzadeh PharmD, PhD Candidate, et al.
Published: (2016-10-01)