Ventricular performance and Na+-K+ ATPase activity are reduced early and late after myocardial infarction in rats

Ventricular performance and Na+-K+ ATPase activity are reduced early and late after myocardial infarction in rats

Myocardial infarction leads to compensatory ventricular remodeling. Disturbances in myocardial contractility depend on the active transport of Ca2+ and Na+, which are regulated by Na+-K+ ATPase. Inappropriate regulation of Na+-K+ ATPase activity leads to excessive loss of K+ and gain of Na+ by the c...

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Bibliographic Details
Main Authors: I. Stefanon, J.R. Cade, A.A. Fernandes, R.F. Ribeiro Junior, G.P. Targueta, J.G. Mill, D.V. Vassallo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Heart failure
Ouabain
Na+-K+ ATPase
Myocardial infarction
Calcium handling
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000005

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