Metabolic Dysregulation Contributes to the Progression of Alzheimer’s Disease

Metabolic Dysregulation Contributes to the Progression of Alzheimer’s Disease

Alzheimer’s disease (AD) is an incurable neurodegenerative disease. Numerous studies have demonstrated a critical role for dysregulated glucose metabolism in its pathogenesis. In this review, we summarize metabolic alterations in aging brain and AD-related metabolic deficits associated with glucose...

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Bibliographic Details
Main Authors:	Xu Yan, Yue Hu, Biyao Wang, Sijian Wang, Xinwen Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Neuroscience
Subjects:	Alzheimer’s disease glucose metabolism dysregulation glycolysis dysfunction TCA cycle and OXPHOS deficits pentose phosphate pathway impairment
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2020.530219/full

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