A unique role for galectin-9 in angiogenesis and inflammatory arthritis
Abstract Background Galectin-9 (Gal-9) is a mammalian lectin secreted by endothelial cells that is highly expressed in rheumatoid arthritis synovial tissues and synovial fluid. Roles have been proposed for galectins in the regulation of inflammation and angiogenesis. Therefore, we examined the contr...
Main Authors: | Martin J. O’Brien, Qiang Shu, W.Alexander Stinson, Pei-Suen Tsou, Jeffrey H. Ruth, Takeo Isozaki, Phillip L. Campbell, Ray A. Ohara, Alisa E. Koch, David A. Fox, M. Asif Amin |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
|
Series: | Arthritis Research & Therapy |
Online Access: | http://link.springer.com/article/10.1186/s13075-018-1519-x |
Similar Items
-
Galectins in Endothelial Cell Biology and Angiogenesis: The Basics
by: Victor L. Thijssen
Published: (2021-09-01) -
VEGFR1 and VEGFR2 involvement in extracellular galectin-1- and galectin-3-induced angiogenesis.
by: Nicky D'Haene, et al.
Published: (2013-01-01) -
The role of galectin-3 and galectin-9 in the chronic inflammation of rheumatoid arthritis
by: Bik, Magadelena Anna
Published: (2009) -
Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors.
by: Julia Etulain, et al.
Published: (2014-01-01) -
Transcriptional Regulation of Galectin 15 (LGALS15): An Implantation-Related Galectin Uniquely Expressed in the Uteri of Sheep and Goats
by: Lewis, Shaye K.
Published: (2010)