High-Mobility Group Nucleosome-Binding Protein 1 Mediates Renal Fibrosis Correlating with Macrophages Accumulation and Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy Mice Model

High-Mobility Group Nucleosome-Binding Protein 1 Mediates Renal Fibrosis Correlating with Macrophages Accumulation and Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy Mice Model

Background/Aim: Renal fibrosis is essential for the progression of diabetic nephropathy (DN). Macrophages accumulate in diabetic kidneys and are involved in epithelial-to-mesenchymal transition (EMT), a vital mechanism leading to renal fibrosis. Recently, high-mobility group nucleosome-binding prote...

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Bibliographic Details
Main Authors: Jiali Yu, Rong Dong, Jingjing Da, Jiayu Li, Fuxun Yu, Yan Zha
Format: Article
Language:English
Published: Karger Publishers 2019-06-01
Series:Kidney & Blood Pressure Research
Subjects:
Diabetic nephropathy
Fibrosis
Macrophages
Epithelial-to-mesenchymal transition
Online Access:https://www.karger.com/Article/FullText/499877

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