Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes.

Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes.

Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...

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Bibliographic Details
Main Authors:	Alexander S Davis, Isabelle Vergne, Sharon S Master, George B Kyei, Jennifer Chua, Vojo Deretic
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2007-12-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.0030186

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