Melanoma Cell Resistance to Vemurafenib Modifies Inter-Cellular Communication Signals

Melanoma Cell Resistance to Vemurafenib Modifies Inter-Cellular Communication Signals

The therapeutic success of BRAF inhibitors (BRAFi) and MEK inhibitors (MEKi) in BRAF-mutant melanoma is limited by the emergence of drug resistance, and several lines of evidence suggest that changes in the tumor microenvironment can play a pivotal role in acquired resistance. The present study focu...

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Bibliographic Details
Main Authors: Claudio Tabolacci, Martina Cordella, Sabrina Mariotti, Stefania Rossi, Cinzia Senatore, Carla Lintas, Lauretta Levati, Daniela D’Arcangelo, Antonio Facchiano, Stefania D’Atri, Roberto Nisini, Francesco Facchiano
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
melanoma
BRAF inhibitors resistance
secretory signals
inflammation
basigin
Online Access:https://www.mdpi.com/2227-9059/9/1/79

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