Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids

The authors generate EMLOs (elongating multi-lineage organized gastruloids): organoids that self-organize to form compartments with characteristics of the central nervous system, peripheral nervous system, mesenchyme, and gut tube.

Bibliographic Details
Main Authors: Zachary T. Olmsted, Janet L. Paluh
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23294-7
Description
Summary:The authors generate EMLOs (elongating multi-lineage organized gastruloids): organoids that self-organize to form compartments with characteristics of the central nervous system, peripheral nervous system, mesenchyme, and gut tube.
ISSN:2041-1723