PI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia

PI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia

Objective: Hypophagia and increased energy expenditure under inflammatory conditions, such as that observed after bacterial lipopolysaccharide (LPS) administration, are associated with leptin secretion. The hypophagic effect of leptin depends in part on the activation of PI3K signaling pathway. Howe...

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Bibliographic Details
Main Authors: Beatriz C. Borges, David Garcia-Galiano, Rodrigo Rorato, Lucila L.K. Elias, Carol F. Elias
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300035

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