A novel rare sugar inhibitor of murine herpes simplex keratitis

A novel rare sugar inhibitor of murine herpes simplex keratitis

Purpose: To determine the therapeutic efficacy of a novel rare sugar, l-psicose, for the treatment of HSV-1 induced herpetic stromal keratitis (HSK) in a mouse eye model. Methods: One rare sugar l-psicose was assayed for HSV-1 inhibition of in vitro virus adsorption. The IC50 and IC90 values of l-ps...

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Bibliographic Details
Main Authors: Syed Muniruzzaman, Megan McIntosh, Ahamed Hossain, Ken Izumori, Partha S. Bhattacharjee
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Journal of Pharmacological Sciences
Subjects:
Rare sugar
Herpes simplex keratitis
Eye drop
l-psicose
HSV-1
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300561

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