| Summary: | Objective: To explore the uterine artery and fetal umbilical artery hemodynamic change in
patients with HDP. Methods: A total of 80 patients with HDP who came to our hospital from
July, 2015 to July, 2016 for pregnancy examination were included in the study and served as
the observation group, while 80 healthy pregnant women who came for pregnancy examination
in the same period were served as the control group. The pregnant women in the two groups
were performed with sequential color Doppler ultrasound at gestation 30-40 weeks. The twodimensional
ultrasound apparatus was used to detect the uterine artery and umbilical artery. PI,
RI, and S/D were recorded. The fetal BPD, head girth, femur length, and abdominal girth were
measured. ELISA was used to detect 8-iso-PGF2α. The immunoturbidimetry was used to detect
Cys-C and CRP. Results: The uterine artery PI, RI, and S/D in the observation group were
significantly higher than those in the control group. The umbilical artery PI, RI, and S/D in the
observation group were significantly higher than those in the control group. The fetal BPD,
head girth, femur length, and abdominal girth in the observation group were significantly less
than those in the control group. 8-iso-PGF2α, Cys C, and CRP levels in the observation group
were significantly higher than those in the control group. Conclusions: The uterine artery and
umbilical artery blood flow resistance in patients with HDP are significantly elevated, which
can severely affect the placental blood perfusion and fetal growth and development, while the
color Doppler ultrasound can provide a non-invasive diagnosis for fetal distress in uterus.
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