Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation

Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation

Prevention of hepatic fat accumulation may be an important approach for liver diseases due to the increased relevance of hepatic steatosis in this field. This study was conducted to investigate the effects of the antioxidant α-lipoic acid (α-LA) on hepatic steatosis, hepatocellul...

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Bibliographic Details
Main Authors: Cristina Maria Sena, Maria Augusta Cipriano, Maria Filomena Botelho, Raquel Maria Seiça
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
steatosis
oxidative stress
α-lipoic acid
TNF-α
Nrf2 levels
Online Access:http://www.mdpi.com/1422-0067/19/9/2706

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