Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure

Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure

Abstract Alcohol use disorder (AUD) is highly comorbid with depression. Withdrawal from chronic alcohol drinking results in depression and understanding brain molecular mechanisms that drive withdrawal-related depression is important for finding new drug targets to treat these comorbid conditions. H...

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Bibliographic Details
Main Authors: Wei-Yang Chen, Hu Chen, Kana Hamada, Eleonora Gatta, Ying Chen, Huaibo Zhang, Jenny Drnevich, Harish R. Krishnan, Mark Maienschein-Cline, Dennis R. Grayson, Subhash C. Pandey, Amy W. Lasek
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01421-8

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