APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells.

APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells.

Lifelong latent infections of the trigeminal ganglion by the neurotropic herpes simplex virus type 1 (HSV-1) are characterized by periodic reactivation. During these episodes, newly produced virions may also reach the central nervous system (CNS), causing productive but generally asymptomatic infect...

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Bibliographic Details
Main Authors: Giovanna De Chiara, Maria Elena Marcocci, Livia Civitelli, Rafaela Argnani, Roberto Piacentini, Cristian Ripoli, Roberto Manservigi, Claudio Grassi, Enrico Garaci, Anna Teresa Palamara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21085580/?tool=EBI

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