Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study

Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study

Computational studies using mathematical models of the sinoatrial node (SAN) cardiac action potential (AP) have provided important insight into the fundamental nature of cell excitability, cardiac arrhythmias, and potential therapies. While the impact of ion channel dynamics on SAN pacemaking has be...

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Bibliographic Details
Main Authors: Daniel Gratz, Birce Onal, Alyssa Dalic, Thomas J. Hund
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physics
Subjects:
sinoatrial node
synchrony
computational modeling
coupling
ion channel
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2018.00063/full

Internet

https://www.frontiersin.org/article/10.3389/fphy.2018.00063/full

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