Fibronectin Adsorption to Nanopatterned Silicon Surfaces

The possibility of using surface topography for guidance of different biological molecules and cells is a relevant topic that can be applied to a wide research activity. This study investigated the adsorption of fibronectin to a diffraction grated silicon surface. The rectangular grating profile fea...

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Bibliographic Details
Main Authors: I. Salakhutdinov, P. VandeVord, O. Palyvoda, H. Matthew, G. Tatagiri, H. Handa, G. Mao, G. W. Auner, G. Newaz
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2008/543170
Description
Summary:The possibility of using surface topography for guidance of different biological molecules and cells is a relevant topic that can be applied to a wide research activity. This study investigated the adsorption of fibronectin to a diffraction grated silicon surface. The rectangular grating profile featured a controlled surface with 350 nm period and a corrugation depth of 90 nm. Results demonstrated that the controlled surface had a significantly positive effect on the fibronectin binding. Thus, nanoscale surface topography can enhance fibronectin binding.
ISSN:1687-4110
1687-4129