The molecular mechanism of nuclear transport revealed by atomic-scale measurements

The molecular mechanism of nuclear transport revealed by atomic-scale measurements

Nuclear pore complexes (NPCs) form a selective filter that allows the rapid passage of transport factors (TFs) and their cargoes across the nuclear envelope, while blocking the passage of other macromolecules. Intrinsically disordered proteins (IDPs) containing phenylalanyl-glycyl (FG)-rich repeats...

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Bibliographic Details
Main Authors: Loren E Hough, Kaushik Dutta, Samuel Sparks, Deniz B Temel, Alia Kamal, Jaclyn Tetenbaum-Novatt, Michael P Rout, David Cowburn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
nuclear magnetic resonance
nuclear pore
transport factors
nucleoporins
Online Access:https://elifesciences.org/articles/10027

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