Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy.

Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy.

Long-acting nanoformulated antiretroviral therapy (nanoART) induces a range of innate immune migratory, phagocytic and secretory cell functions that perpetuate drug depots. While recycling endosomes serve as the macrophage subcellular depots, little is known of the dynamics of nanoART-cell interacti...

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Bibliographic Details
Main Authors: Andrea L Martinez-Skinner, Mariluz A Araínga, Pavan Puligujja, Diana L Palandri, Hannah M Baldridge, Benson J Edagwa, JoEllyn M McMillan, R Lee Mosley, Howard E Gendelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696780?pdf=render

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