Pharmacognostical studies of Smilax aspera Linn. – A herbal drug

Background: Smilax aspera L. (sarsaparilla or prickly ivy) is a perennial climber from the family Smilacaceae. Its root and rhizome are used as alterative, demulcent, depurative, diaphoretic, diuretic, stimulant and tonic. Objective: To perform standardization of root and rhizome of S. aspera for au...

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Main Authors: Satish Patel, B Biswas, K Rambabu, E N Sundaram, Renu Arya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Research in Homoeopathy
Subjects:
Online Access:http://www.ijrh.org/article.asp?issn=0974-7168;year=2020;volume=14;issue=4;spage=260;epage=266;aulast=Patel
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spelling doaj-4ec65a37672649bd97cc598da960bce92021-01-08T03:23:24ZengWolters Kluwer Medknow PublicationsIndian Journal of Research in Homoeopathy0974-71682020-01-0114426026610.4103/ijrh.ijrh_13_20Pharmacognostical studies of Smilax aspera Linn. – A herbal drugSatish PatelB BiswasK RambabuE N SundaramRenu AryaBackground: Smilax aspera L. (sarsaparilla or prickly ivy) is a perennial climber from the family Smilacaceae. Its root and rhizome are used as alterative, demulcent, depurative, diaphoretic, diuretic, stimulant and tonic. Objective: To perform standardization of root and rhizome of S. aspera for authentication and identification of raw drug by pharmacognostical, physiochemical, powder and finish product evaluation. Materials and Methods: Air-dried rhizome and roots were boiled, sectioned and stained for macroscopical and microscopical analysis. For physicochemical studies, rhizome and roots were coarsely powdered and subjected for determination of extractive values, ash values, chemical constituents, weight per millilitre, alcohol content, total solids and loss on drying. Finished product analyses (chromatographic studies, sediments, pH and total solid) were also undertaken. Results: The root was longitudinally wrinkled, about 3 mm in diameter with numerous branching, rootless, tough and flexible. Cortex consisted of 18–20 rows of parenchymatous cells; xylem and phloem were arranged in a radiate manner. Rhizome was wrinkled, hard and brown externally and white or light-yellow internally. The outer cortex consisted of polygonal parenchymatous cells. The findings of physicochemical determination of raw drugs including maximum extractive values in alcohol were 5.67% w/w, 0.1% w/w foreign matter, 8.90% w/w moisture content, 10.60% w/w total ash, etc., and finished product parameter showed pH near to 7, total solid 1.07% w/v and 50% v/v alcohol content. Conclusion: The data represented in this article may be used as distinctive diagnostic characters for proper identification, authentication of raw drug to ensure purity, quality and efficacy of drug S. aspera.http://www.ijrh.org/article.asp?issn=0974-7168;year=2020;volume=14;issue=4;spage=260;epage=266;aulast=Patelpharmacognosyphysicochemicalsarsaparillasmilax asperastandardisation
collection DOAJ
language English
format Article
sources DOAJ
author Satish Patel
B Biswas
K Rambabu
E N Sundaram
Renu Arya
spellingShingle Satish Patel
B Biswas
K Rambabu
E N Sundaram
Renu Arya
Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
Indian Journal of Research in Homoeopathy
pharmacognosy
physicochemical
sarsaparilla
smilax aspera
standardisation
author_facet Satish Patel
B Biswas
K Rambabu
E N Sundaram
Renu Arya
author_sort Satish Patel
title Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
title_short Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
title_full Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
title_fullStr Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
title_full_unstemmed Pharmacognostical studies of Smilax aspera Linn. – A herbal drug
title_sort pharmacognostical studies of smilax aspera linn. – a herbal drug
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Research in Homoeopathy
issn 0974-7168
publishDate 2020-01-01
description Background: Smilax aspera L. (sarsaparilla or prickly ivy) is a perennial climber from the family Smilacaceae. Its root and rhizome are used as alterative, demulcent, depurative, diaphoretic, diuretic, stimulant and tonic. Objective: To perform standardization of root and rhizome of S. aspera for authentication and identification of raw drug by pharmacognostical, physiochemical, powder and finish product evaluation. Materials and Methods: Air-dried rhizome and roots were boiled, sectioned and stained for macroscopical and microscopical analysis. For physicochemical studies, rhizome and roots were coarsely powdered and subjected for determination of extractive values, ash values, chemical constituents, weight per millilitre, alcohol content, total solids and loss on drying. Finished product analyses (chromatographic studies, sediments, pH and total solid) were also undertaken. Results: The root was longitudinally wrinkled, about 3 mm in diameter with numerous branching, rootless, tough and flexible. Cortex consisted of 18–20 rows of parenchymatous cells; xylem and phloem were arranged in a radiate manner. Rhizome was wrinkled, hard and brown externally and white or light-yellow internally. The outer cortex consisted of polygonal parenchymatous cells. The findings of physicochemical determination of raw drugs including maximum extractive values in alcohol were 5.67% w/w, 0.1% w/w foreign matter, 8.90% w/w moisture content, 10.60% w/w total ash, etc., and finished product parameter showed pH near to 7, total solid 1.07% w/v and 50% v/v alcohol content. Conclusion: The data represented in this article may be used as distinctive diagnostic characters for proper identification, authentication of raw drug to ensure purity, quality and efficacy of drug S. aspera.
topic pharmacognosy
physicochemical
sarsaparilla
smilax aspera
standardisation
url http://www.ijrh.org/article.asp?issn=0974-7168;year=2020;volume=14;issue=4;spage=260;epage=266;aulast=Patel
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