Emergence and evolution of an interaction between intrinsically disordered proteins

Emergence and evolution of an interaction between intrinsically disordered proteins

Protein-protein interactions involving intrinsically disordered proteins are important for cellular function and common in all organisms. However, it is not clear how such interactions emerge and evolve on a molecular level. We performed phylogenetic reconstruction, resurrection and biophysical char...

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Bibliographic Details
Main Authors: Greta Hultqvist, Emma Åberg, Carlo Camilloni, Gustav N Sundell, Eva Andersson, Jakob Dogan, Celestine N Chi, Michele Vendruscolo, Per Jemth
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
intrinsically disordered proteins
Evolution
Protein-protein interaction
Affinity
phylogenetic reconstruction
molecular dynamics
Online Access:https://elifesciences.org/articles/16059

Internet

https://elifesciences.org/articles/16059

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