Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome

Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome

Rothmund-Thomson syndrome is a genetic disorder with characteristic findings in childhood as well as a predisposition to osteosarcoma, skin cancer, and hematological malignancy. We present the first reported case of duodenal malignancy in a patient with Rothmund-Thompson syndrome. An enlarged Vircho...

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Main Authors: Kara Nadeau, Michele Brule
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Genetics
Online Access:http://dx.doi.org/10.1155/2018/7536832
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spelling doaj-4ebd33483c5e4044ac102cfa742401132020-11-24T21:06:20ZengHindawi LimitedCase Reports in Genetics2090-65442090-65522018-01-01201810.1155/2018/75368327536832Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson SyndromeKara Nadeau0Michele Brule1Faculty of Medicine, University of Ottawa, Ottawa, Ontario, CanadaDepartment of General Surgery, Northern Ontario School of Medicine, Sudbury, Ontario, CanadaRothmund-Thomson syndrome is a genetic disorder with characteristic findings in childhood as well as a predisposition to osteosarcoma, skin cancer, and hematological malignancy. We present the first reported case of duodenal malignancy in a patient with Rothmund-Thompson syndrome. An enlarged Virchow’s node was noted and an advanced duodenal adenocarcinoma was diagnosed shortly thereafter. The features of Rothmund-Thomson syndrome are discussed, as well as current management and screening guidelines for duodenal adenocarcinoma.http://dx.doi.org/10.1155/2018/7536832
collection DOAJ
language English
format Article
sources DOAJ
author Kara Nadeau
Michele Brule
spellingShingle Kara Nadeau
Michele Brule
Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
Case Reports in Genetics
author_facet Kara Nadeau
Michele Brule
author_sort Kara Nadeau
title Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
title_short Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
title_full Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
title_fullStr Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
title_full_unstemmed Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome
title_sort gastrointestinal malignancy presenting with a virchow’s node in a patient with rothmund-thomson syndrome
publisher Hindawi Limited
series Case Reports in Genetics
issn 2090-6544
2090-6552
publishDate 2018-01-01
description Rothmund-Thomson syndrome is a genetic disorder with characteristic findings in childhood as well as a predisposition to osteosarcoma, skin cancer, and hematological malignancy. We present the first reported case of duodenal malignancy in a patient with Rothmund-Thompson syndrome. An enlarged Virchow’s node was noted and an advanced duodenal adenocarcinoma was diagnosed shortly thereafter. The features of Rothmund-Thomson syndrome are discussed, as well as current management and screening guidelines for duodenal adenocarcinoma.
url http://dx.doi.org/10.1155/2018/7536832
work_keys_str_mv AT karanadeau gastrointestinalmalignancypresentingwithavirchowsnodeinapatientwithrothmundthomsonsyndrome
AT michelebrule gastrointestinalmalignancypresentingwithavirchowsnodeinapatientwithrothmundthomsonsyndrome
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