Behavioral and Neurochemical Effects of Alpha-Lipoic Acid in the Model of Parkinson’s Disease Induced by Unilateral Stereotaxic Injection of 6-Ohda in Rat

Behavioral and Neurochemical Effects of Alpha-Lipoic Acid in the Model of Parkinson’s Disease Induced by Unilateral Stereotaxic Injection of 6-Ohda in Rat

This study aimed to investigate behavioral and neurochemical effects of α-lipoic acid (100 mg/kg or 200 mg/kg) alone or associated with L-DOPA using an animal model of Parkinson’s disease induced by stereotaxic injection of 6-hydroxydopamine (6-OHDA) in rat striatum. Motor behavior was assessed by m...

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Bibliographic Details
Main Authors: Dayane Pessoa de Araújo, Caren Nádia Soares De Sousa, Paulo Victor Pontes Araújo, Carlos Eduardo de Souza Menezes, Francisca Taciana Sousa Rodrigues, Sarah Souza Escudeiro, Nicole Brito Cortez Lima, Manoel Claúdio Azevedo Patrocínio, Lissiana Magna Vasconcelos Aguiar, Glauce Socorro de Barros Viana, Silvânia Maria Mendes Vasconcelos
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/571378

Internet

http://dx.doi.org/10.1155/2013/571378

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