Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D

Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D

Surfactant protein D (SP-D) is expressed in the mucosal secretion of the lung and contributes to the innate host defense against a variety of pathogens, including influenza A virus (IAV). SP-D can inhibit hemagglutination and infectivity of IAV, in addition to reducing neuraminidase (NA) activity vi...

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Bibliographic Details
Main Authors: Mohammed N. Al-Ahdal, Valarmathy Murugaiah, Praveen M. Varghese, Suhair M. Abozaid, Iram Saba, Ahmed Ali Al-Qahtani, Ansar A. Pathan, Lubna Kouser, Béatrice Nal, Uday Kishore
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
innate immunity
influenza A virus
surfactant protein D
pseudotyped lentiviral particles
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01586/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01586/full

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