Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response

Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response

The Zika virus originates from Africa and Asia but is emerging in other parts of the world. It usually causes an asymptomatic or mild, acute infection but can cause serious neurological complications, such as microcephaly and Guillain-Barré syndromes.

Bibliographic Details
Main Authors: Mohammed Mufrrih, Biyao Chen, Shiu-Wan Chan
Format: Article
Language:English
Published: American Society for Microbiology 2021-06-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00361-21
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spelling doaj-4e9e0c481357423283d9c53c7f1249d12021-09-21T20:35:23ZengAmerican Society for MicrobiologymSphere2379-50422021-06-016310.1128/mSphere.00361-21Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP ResponseMohammed Mufrrih0Biyao Chen1Shiu-Wan Chan2https://orcid.org/0000-0002-4018-9309Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester, United KingdomFaculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester, United KingdomFaculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom The Zika virus originates from Africa and Asia but is emerging in other parts of the world. It usually causes an asymptomatic or mild, acute infection but can cause serious neurological complications, such as microcephaly and Guillain-Barré syndromes.https://journals.asm.org/doi/10.1128/mSphere.00361-21
collection DOAJ
language English
format Article
sources DOAJ
author Mohammed Mufrrih
Biyao Chen
Shiu-Wan Chan
spellingShingle Mohammed Mufrrih
Biyao Chen
Shiu-Wan Chan
Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
mSphere
author_facet Mohammed Mufrrih
Biyao Chen
Shiu-Wan Chan
author_sort Mohammed Mufrrih
title Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
title_short Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
title_full Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
title_fullStr Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
title_full_unstemmed Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response
title_sort zika virus induces an atypical tripartite unfolded protein response with sustained sensor and transient effector activation and a blunted bip response
publisher American Society for Microbiology
series mSphere
issn 2379-5042
publishDate 2021-06-01
description The Zika virus originates from Africa and Asia but is emerging in other parts of the world. It usually causes an asymptomatic or mild, acute infection but can cause serious neurological complications, such as microcephaly and Guillain-Barré syndromes.
url https://journals.asm.org/doi/10.1128/mSphere.00361-21
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AT biyaochen zikavirusinducesanatypicaltripartiteunfoldedproteinresponsewithsustainedsensorandtransienteffectoractivationandabluntedbipresponse
AT shiuwanchan zikavirusinducesanatypicaltripartiteunfoldedproteinresponsewithsustainedsensorandtransienteffectoractivationandabluntedbipresponse
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