Serine integrase chimeras with activity in E. coli and HeLa cells

In recent years, application of serine integrases for genomic engineering has increased in popularity. The factor-independence and unidirectionality of these large serine recombinases makes them well suited for reactions such as site-directed vector integration and cassette exchange in a wide variet...

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Bibliographic Details
Main Authors: Alfonso P. Farruggio, Michele P. Calos
Format: Article
Language:English
Published: The Company of Biologists 2014-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/3/10/895