Implications of ACMG guidelines to identify high-risk acute lymphoblastic leukemia patients with hereditary cancer susceptibility syndromes (HCSS) in a highly consanguineous population

Implications of ACMG guidelines to identify high-risk acute lymphoblastic leukemia patients with hereditary cancer susceptibility syndromes (HCSS) in a highly consanguineous population

Abstract Background Hereditary cancer susceptibility syndrome (HCSS) contributes to the cancer predisposition at an early age, therefore, identification of HCSS has found to be crucial for surveillance, managing therapeutic interventions and refer the patients and their families for genetic counsell...

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Bibliographic Details
Main Authors: Sara Aslam, Shabana, Mehboob Ahmed
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Pediatrics
Subjects:
Consanguinity
Hereditary cancer susceptibility syndrome (HCSS)
Risk assessment
ACMG guidelines
Acute lymphoblastic leukemia (ALL)
Online Access:https://doi.org/10.1186/s12887-021-02749-2

Internet

https://doi.org/10.1186/s12887-021-02749-2

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