Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations

Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations

Lymphatic malformations are abnormalities that arise in the developing lymphatic system, most frequently presenting in the head and neck. They are typically treated with sclerotherapy, laser therapy, or surgery for localized lesions. Sirolimus, an inhibitor of the mammalian target of rapamycin, is a...

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Main Authors: Steven Curry, Andrew Logeman, Dwight Jones
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2019/2076798
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spelling doaj-4e88adf5899f45a7a60042b7d78b2f8d2020-11-25T01:11:31ZengHindawi LimitedCase Reports in Otolaryngology2090-67652090-67732019-01-01201910.1155/2019/20767982076798Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic MalformationsSteven Curry0Andrew Logeman1Dwight Jones2Department of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USADepartment of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USADepartment of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USALymphatic malformations are abnormalities that arise in the developing lymphatic system, most frequently presenting in the head and neck. They are typically treated with sclerotherapy, laser therapy, or surgery for localized lesions. Sirolimus, an inhibitor of the mammalian target of rapamycin, is a relatively new medical therapy for the treatment of vascular malformations. This case report presents the improvements and complications seen in a female infant who was diagnosed with a large lymphatic malformation on prenatal ultrasound and has been treated with sirolimus during the first 9 months of life.http://dx.doi.org/10.1155/2019/2076798
collection DOAJ
language English
format Article
sources DOAJ
author Steven Curry
Andrew Logeman
Dwight Jones
spellingShingle Steven Curry
Andrew Logeman
Dwight Jones
Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
Case Reports in Otolaryngology
author_facet Steven Curry
Andrew Logeman
Dwight Jones
author_sort Steven Curry
title Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
title_short Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
title_full Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
title_fullStr Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
title_full_unstemmed Sirolimus: A Successful Medical Treatment for Head and Neck Lymphatic Malformations
title_sort sirolimus: a successful medical treatment for head and neck lymphatic malformations
publisher Hindawi Limited
series Case Reports in Otolaryngology
issn 2090-6765
2090-6773
publishDate 2019-01-01
description Lymphatic malformations are abnormalities that arise in the developing lymphatic system, most frequently presenting in the head and neck. They are typically treated with sclerotherapy, laser therapy, or surgery for localized lesions. Sirolimus, an inhibitor of the mammalian target of rapamycin, is a relatively new medical therapy for the treatment of vascular malformations. This case report presents the improvements and complications seen in a female infant who was diagnosed with a large lymphatic malformation on prenatal ultrasound and has been treated with sirolimus during the first 9 months of life.
url http://dx.doi.org/10.1155/2019/2076798
work_keys_str_mv AT stevencurry sirolimusasuccessfulmedicaltreatmentforheadandnecklymphaticmalformations
AT andrewlogeman sirolimusasuccessfulmedicaltreatmentforheadandnecklymphaticmalformations
AT dwightjones sirolimusasuccessfulmedicaltreatmentforheadandnecklymphaticmalformations
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